elvitegravir

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Elvitegravir is an integrase inhibitor. Integrase inhibitors target an enzyme called integrase which HIV uses to integrate its genetic code into human cells. Because this is a different point of action to that targeted by other drug classes, there is a good chance that people who have failed several prior treatment regimens will benefit from this drug, especially if it is combined with an optimised background regimen.

Basic info


Generic name elvitegravir
Brand name Vitekta (UK & US)
Also known as EVT
Drug class Integrase Inhibitors
Pediatric dosing? Available in doses suitable for children and/or young people.
Availability in Australia Not yet available on the Pharmaceutical Benefits Scheme (PBS), however an application for PBS approval has been lodged.
This drug may be available through clinical trials in Australia.
You may be able to import this drug from overseas for your personal use.
Formulation
Links:


Taking it

Like most anti-HIV drugs, elvitegravir must be taken in combination with other drugs to be completely effective. Commonly, elvitegravir is combined with one other nucleoside (NRTI) drug and either a protease inhibitor or non-nucleoside, although other combinations are sometimes used. Your doctor will advise you on the right combination of drugs to suit your circumstances.


Dosage

150mg once daily and needs boosting with Cobicistat or Ritonavir (Norvir)

Regardless of what you read on this website or elsewhere, you should always take your medications according to your doctor's instructions. If you're unsure, speak to your doctor or pharmacist.


With or without food

elvitegravir should be taken with food

Side effect

All drugs can produce side effects in some people. These may be mild, moderate or severe, so you should be aware of potential side effects before starting any drug, and speak to your doctor if you experience side effects that concern you.


Interactions with other drugs

For more information follow the above link to AIDS MEDS & Poz.